Rutgers Combined Linkage-Physical Map

We have constructed de novo a high-resolution genetic map that includes the largest set of polymorphic markers for which genotype data are publicly available:

• that combines genotype data from both the CEPH and deCODE pedigrees (for some markers)
• that incorporates SNPs
• that also incorporates sequence-based positional information.

The position of most markers on our map is corroborated by both genomic sequence and recombination-based data. This specific combination of features maximizes marker inclusion, coverage, and resolution, making this map uniquely suited as a comprehensive resource for determining genetic map information (order and distances) for any large set of polymorphic markers.

Please use this PubMed reference when referring to the Rutgers Maps.

This set of combined genotype data (exclusive of the deCODE data) and maps has been incorporated into the Map-O-Mat web-based linkage mapping server for analysis of human linkage maps.

Map-O-Mat facilitates the verification of marker order and calculation of map distances for custom mapping sets by running the Cri-Map program for linkage analysis using the genotype data described in this manuscript.

Please use this PubMed reference when referring to Map-O-Mat.