I am working with a four year old boy who is diagnosed with deletion 1Q syndrome. Over the past year, he has demonstrated minimal progress in speech and language therapy. He does not consistently respond to stimuli. In some areas, he appears to have lost skills. Is this typical of the syndrome?

My wife is 37 years old and 22 weeks pregnant with a girl. The amnio showed a inversion: 46, XX, inv(1)(p13,q12). Please advise if you have any information on what this could mean. We have been unable to find any data on similar inversions. Regardless of any information you find, we plan to share our information with you when the baby is born. Thank you very much.

Chromosome 1p deletion - does any one know of outcome or
any parents wanting to share experiences please contact me

I am working on skin cancer group here at national cancer institute, usa.
I would like to obtain cell lines that has deletion in 1p34.1 to 1p34.3 region.
I also like to find out any known human disease(s) that are related to abnormality of this region.
Any cancer related info regarding this region are very much needed also.
Thank you all

I have recently been asked to see a delightful 31/2 year old girl with what turns out to be a deletion of 1q24.2.
I would like to correspond with anyone who has has experience with a similar child.
thanks
PM.MacLeod M.D.

I am doing a project on LSD and I would like some information about
LSD induced damage to chromosome one.

Thank you.

My friend's baby has just been diagnosed with leukemia and a condition called Pennsylvania Chromosome. Can you explain this to me. Thank you.

I have queries regarding trisomy 1 (mosaicism-found in skin but not in blood). Could you help me with links or data which would help me guide my patient and search literature

I hav e a question about Chromosome 1 that was asked in a Biology class. We're studying Trisomies and I'm wondering if there is any reason why a trisomy could not occur with Chromosome 1? Is there a specific reason why Trisomy 13, 18 and 21 are more common? Thanks for any response. Take care
-George

Couple ?'s
Who discovered chromosome 1?
What does chrom 1 do and control?
What are its gene mutations?
What are its genetic disorders?Can u send me maps and pictures of chromosome 1?
What's so interesting about this chromosome?

I have been asked to see a child who has the diagnosis of "deletion of chromosone #1". He seems to be having some vision concerns. I was researching this diagnosis and was unable to find characteristics, including vision problems. I would appriciate any input concerning the field of vision with children with this diagnosis. Thank You

sir,
i would like to know,is it any method available for telomere
maping ? how we can calculate age of a human being?
is there any relation between telomere and chromosome for age determination?
if you provide me these infomation , i will remain grateful to you.
thanks
mahfooz
cdfd, reserch assistant

Hopefully you can help me or at least direct me to someone who might
be able to help. My son Tony is 9 yrs old. He was born with
a balanced chromosome translocation 1 and 15. His disablilities
consist of fused elbows and wrists both arms, (doctors say arthrogryposis)
sm finger both hands and ring finger both hands bent, (were able to straigten
at one point around age 1 but didn't stay. Tendons TIGHT) PDD-NOS (very slight
version of autism) sm head, (soft spot fused very early and frontal fused before 1)
slight talking, (just really started recently) between ages 1-4, failure to thrive,
from 1 week - 6months, confused sphintor (had to help go to the bathroom. Felt his
intestines had lessions or slightly twisted. Tony loves to sit upside down on
his head and flap his arms.
Dr. Yang was his genetic specialist here in Sacramento, CA and before
changing to Kaiser he informed me that he felt they had discovered
a new gene in chromosome 1 but I had to find a team of doctors
who would want to persue this finding. He has no problem with
sharing the information and all.
Tony's father has the same translocation and paternal grandpa (deceased now)
but not his older brother.

If you could help me I would greatly appreciate it.
Thank you

Renee Daw
6353 Villa Drive
Sacramento, CA 95842
(916)348-7061 hm
(916)338-4304 message
way2nay@hotmail.com

My little girl is now 4yrs old and was diagnosed with chromosome 1 p deletion...she seems to be over all her medical conditions(ex. patent ductus arteriosis,heart murmur and pulmonary hypertension)she has been medically healthy for about 2 yrs but she still only talks minimally and does not walk...anyone out there who can tell me what to expect?

My brother and sister-n-law recently gave birth to a
daughter with a chromosome 1 P36.22 deletion. She is
currently in the NICU being treated for medical problems
(including an intestinal blockage requiring surgery,
congenital heart problems, grade 1 brain bleed, and
enlarged brain ventricles; to name a few). Unfortunately
their doctors have not been able to give them much
information regarding this abnormality. We would appreciate
any information regarding prognosis, expected life span,
and what to expect in general (special needs,
growth/development, etc.). Any information you can provide
would be greatly appreciated.

I am seeing a 3 year, 6 month old female child for speech and language therapy. She presents with extreme attention deficits and hyperactivity. She is essentially nonverbal, with only a few rote phrases that are used inappropriately. I referred her parents to a pediatric neurologist, who in turn referred for chromosomal testing. the results of the cytogenic analysis revealed balanced translocation involving the distal portion of 1q to the distal short arm of chromosome 17. The other cell line revealed the same 1q translocation to the distal long arm of 17. Can anyone help me to answer her parents questions regarding what this all means?

can you please help me about 3 human chromosomes and
involving with monosomy and trisomy.

i would like to participate in this discussion

My 3-month-old daughter was recently diagnosed withchromosome 1p deletion syndrome, specifically "a very small deletion from band p36.3 to pter." She has been diagnosed with mild/moderate hearing loss, mild ventriculomegaly (not requiring shunt surgery), a small PDA (2mm), infrequent PVCs, hypotonia, and some developmental delays. Any information you could send us pertaining to this diagnosis would be most appreciated including information on life expectancy, potential motor/mental development, and any other information pertaining to this syndrome. Thank you very much, Annette Feuss

Hi Folks, I have a query. Is there any possiblity to get subclones of region 1p36.Could anyone tell me who is a good resource for this region of chromosome 1.Do e-mail me with the info.
many thanks
shaji

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I am looking for information, my daughter was diagnosed with a micro deletion of the long arm of chromosome one. There seems to be very little information available as to what this part of the chromosome represents. As to date she has Mild Pulmonary stenosis, Bilateral 4th Nerve Palsy, A mild skull defect, she experienced mild speech delay, she also experiened a delay in gross and fine motor skills.
She also had a Ventricular septal defect which closed spontaneously. My concerns now are with her general development , at 6 she seems to be lagging behind her peers at school and needs one on one attention to help her with her work.Her medical problems seem to have subsided , but now I need to find out what is in store for her with her learning capabilities. Any information sent would be greatly received. Lack of information is proving difficult, especially with schools and trying to get extra help.

for my biology class we are talking about different kinds of gentic disorders could some tell me some that have to with chromosome 1
this would help me alot
thank you

My little brother was born with a extra piece on his
#1 chromosome. Is there a name for this type of disorder?
My mother told me the doctors told her in 1987 that this
was a rare disorder and he would not live past the age of one.
He is now 16 years old. The reason why I'm asking is because
I would like to know the name of his disorder when I explain
his situation to people.

Hi everyone
I read the book Genome: the Autobiography of a species in 23 Chapters by Matt Ridley. I'm supposed to write a research paper on chromosome 1 after reading that book. Unfortunately, there is nothing exciting I can write about chromosome 1. Can someone give me some ideas.
Thank you.

Why is the loss of chromosome material result in more zygote deaths than the addition?