The Rutgers Combined Linkage-Physical Map of The Human Genome

We have constructed de novo a high-resolution genetic map that includes the largest set of polymorphic markers for which genotype data are publicly available, that combines genotype data from both the CEPH and deCODE pedigrees (for some markers), that incorporates SNPs, and that also incorporates sequence-based positional information. The position of most markers on our map is corroborated by both genomic sequence and recombination-based data. This specific combination of features maximizes marker inclusion, coverage, and resolution, making this map uniquely suited as a comprehensive resource for determining genetic map information (order and distances) for any large set of polymorphic markers.

This set of combined genotype data (exclusive of the deCODE data) and maps has been incorporated into the MAP-O-MAT web-based linkage mapping server for analysis of human linkage maps (Kong, X. and Matise T., 2005). MAP-O-MAT facilitates the verification of marker order and calculation of map distances for custom mapping sets by running the CRI-MAP program for linkage analysis using the genotype data described in this manuscript.

Click Here for the Second Generation version. This is the Build 36 version of our maps with > 28,000 markers (10/9/06).

Click Here for the version B35.1. This is the Build 35 version of our maps with Build 36 physical positions provided (10/9/06).

Click Here for the original published version (Build 34, 11/2004).

Click Here for comparison of physical positions assigned with Build 34 and 35.