A Quick Guide to Multimap by Daniel E. Weeks Basic Steps for running Multimap on CEPH-family data in LINKAGE-format: (if your data is already in CRI-MAP format skip to 3). 1) Use 'lnktocri' to convert the pedfile to chrXX.gen, where 'XX' is the number of the chromosome (or any integer). You need to know the number of families and number of markers in your data file (Hint: If you do not know the number of families, put in a number larger and 'lnktocri' will tell you the number of families). 2) Insert the marker names into the chrXX.gen file. It is better if the names are 8 or less characters long. (grep them out of the 'datain.dat' file % grep # datain.dat > names and edit names to remove the leading columns If you have the Unix command 'colrm' availalbe, you can do % colrm 1 8 < names > names2 and paste 'names2' into 'chrXX.gen'.) 3) Run 'lispcri' to create 'chrXX.dat' % lispcri XX prepare 4) Run 'makenames' to create the 'chrXX.names' file. % makenames chrXX.loc > chrXX.names 5) Start up the Lisp interpreter % clisp 6) Run 'create-input-file' to create the input file 'chrXX.input' > (create-input-file) If you need to customize your run and you chose defaults when creating the input file, editing the input file before step 7. 7) Start the Multimap run > (multimap XX) NOTE: To exit from the Lisp interpreter, type > (quit) To exit from the debugger and return to main LISP prompt, type > abort